[A*K*A DILT (drug-induced liver toxicity)]
Here are a few drugs that you may have encountered or are familiar with.
Just a reminder :Too much of something can be dangerous or too little of something can also be dangerous!!
Drugs that may cause ACUTE DOSE-DEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis) acetaminophen
salicylates (doses over 2 grams daily)
salicylates (doses over 2 grams daily)
Drugs that may cause ACUTE DOSE-INDEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis)
(resembling acute viral hepatitis)
acebutolol
atenolol
ketoconazole
naproxen
sulfonamides
ethambutol
penicillins
tricyclic antidepressants
ibuprofen
and more.....ketoconazole
naproxen
sulfonamides
ethambutol
penicillins
tricyclic antidepressants
ibuprofen
Drugs that may cause ACUTE FATTY INFILTRATION OF THE LIVER
adrenocortical steroids
phenothiazines
sulfonamides
antithyroid drugs
phenytoin
tetracyclines
isoniazid
salicylates
valproic acid
methotrexate
Drugs that may cause CHOLESTATIC JAUNDICE
erythromycin
amoxicillin/clavulanate
diazepam
gold
cephalosporins
oral contraceptivesamoxicillin/clavulanate
diazepam
gold
cephalosporins
methyltestosterone
tricyclic antidepressants
nonsteroidal
anti-inflammatory drugs
and more......
Drugs that may cause LIVER GRANULOMAS
(chronic inflammatory nodules)
gold
phenytoin
aspirin
carbamazepine
isoniazid
sulfonamides phenytoin
aspirin
carbamazepine
isoniazid
penicillin
and more.....
Drugs that may cause CHRONIC LIVER DISEASE
acetaminophen (chronic use, large doses)
dantrolene
methyldopadantrolene
isoniazid
nitrofurantoin
Drugs that may cause LIVER CIRRHOSIS or FIBROSIS
(scarring)
methotrexateterbinafine HCI (Lamisil, Sporanox)
nicotinic acid
Drugs that may cause CHRONIC CHOLESTASIS
(resembling primary biliary cirrhosis)
chlorpromazine/valproic acid (combination)
imipramine
thiabendazole
phenothiazines
tolbutamide
chlorpropamide/erythro-mycin (combination)
phenytoin
imipramine
thiabendazole
phenothiazines
tolbutamide
chlorpropamide/erythro-mycin (combination)
phenytoin
Drugs that may cause LIVER TUMORS
(benign and malignant)
anabolic steroids
oral contraceptives
thorotrast
danazol
testosterone
oral contraceptives
thorotrast
danazol
testosterone
Drugs that may cause DAMAGE TO LIVER BLOOD VESSELS
anabolic steroids
vitamin A (excessive doses)
carmustine
mitomycin
cyclophosphamide/cyclo-sporine (combination)
oral contraceptives
and more.....
*Some drugs are listed in more than one category
2 comments:
This is very helpful information! I take tylenol and have always been concerned with what other drugs could lead to an interaction. And plus, I recognized a few drugs listed but did not know much about them and now I do. Also, The websites were very helpful. Thanks!
I only thought that most toxic interactions would be with prescribed medications only. It is very alarming that many OTC medications have dangerous interactions and most people are completely unaware.
Post a Comment